In Texas, the gang leaded by the black market dealer Abby faces a group of renegade militaries leaded by Captain Muldoon in an abandoned military base. During their shootout, Abby shoots a recipient of biological weapon, releasing an experimental highly-contagious gas that turns humans to flesh-eating zombies. Meanwhile, in the local hospital, Dr. Block sees an epidemic with many patients with the same nasty symptoms. When the outbreak affects most of the local population, a group of people with immunity leaded by the mechanic Wray, Sheriff Hague, the stripper Cherry and the Dr. Dakota, fight to survive and become the last hope to save the world.

Rose McGowan originally suggested her friend Rey-Phillip Santos for the role of El Wray. Instead it went to Freddy Rodríguez.

Dr. Dakota Block:
No more dead bodies for Daddy tonight.

Incorrectly regarded as goofs: As ‘Planet Terror’ is an homage to the old, low budget Grindhouse films of the 70's and 80's, there are many deliberate errors by the filmmaker to give an authentic Grindhouse feel.

Written by Robert Rodriguez