Genoan navigator Christopher Columbus has a dream to find an alternative route to sail to the Indies, by traveling west instead of east, across the unchartered Ocean sea. After failing to find backing from the Portugese, he goes to the Spanish court to ask Queen Isabella and King Ferdinand for help. After surviving a grilling from the Head of the Spanish Inquisition Tomas de Torquemada, he eventually gets the blessing from Queen Isabella and sets sail in three ships to travel into the unknown. Along the way he must deal with sabotage from Portugese spies and mutiny from a rebellious crew.

To reach high authenticity the whole crew crossed the Atlantic Ocean from Spain to America in three original ships provided by the Spanish government.

Christopher Columbus:
[to the Torquemada, the Grand Inquisitor] I recall our blessed Lord said: here is a new commandment I give to you. That you love one another as I loved you. Surely it is not blasphemy to take that message to the shores of Africa or across the ocean sea.