"Moesha" is a sitcom (which, in later years, took more of a dramatic turn) that follows the life and times of a black teenager living in the Leimert Park section of Los Angeles, CA. For years since her mother died, Moesha Mitchell has taken care of her father Frank and younger brother Myles. So when a teacher at her school, Dee, marries Frank, Moesha feels her territory being encroached upon by a new step mother. As time went on, the two females of the house would learn to appreciate and cherish each other's presence. Moesha's boy-crazy best friends Kim and Niecy as well as her eternally hungry neighbor and pal Hakeem are there to support Mo throughout all of the drama she finds herself in--and there's always plenty. Andell, a local smoothie shop owner, is another close confidante of Moesha's, lending her wisdom to the teen when needed. Over the years, it was Frank who Moesha would clash with most. He has quite a hard time witnessing his "pumpkin" grow up, and often hates her boyfriends, most notably Q. After graduating from high school, Moesha attends classes at "Cal U" with Hakeem and Niecy, and back at home, the entire family struggles with a startling revelation about Moesha's cousin, Dorian.

There are four different versions of the theme song.

Myles:
Dorian, you can keep begging until Lil' Kim comes out with a gospel album. It ain't gonna happen.