Actor Michael Muhney was initially up for the role of JD, but was told he wasn't quirky enough for the role.

[to an annoying patient]


Dr. Cox:
Okay, think of what little patience I have as... oh, I don't know... your virginity. You always thought it would be there, until that night Junior Year when you were feeling a little down about yourself and your pal Kevin, who just wanted to be friends... well, he dropped by, and he brought a copy of "About Last Night" and a four-pack of Bartles & Jaymes and woo hoo hoo, it was gone forever - just like my patience is now.


Jill Tracy:
So you do scary little speeches. How adorable!

Incorrectly regarded as goofs: The x-ray with the show's title shown in the beginning is turned the wrong way: the heart should be seen on the right hand side. This was an intentional mistake put in by creator Bill Lawrence to represent the core idea of the show: young doctors in over their heads. Bill Lawrence reminds viewers that this goof was completely intentional in interviews, DVD commentaries, and virtually any other available opportunity.

Written and Performed by Lazlo Bane
(Main theme)