The misadventures of Stan Smith and his wacky family. Stan: Stan works for the CIA, and is constantly on the look-out for terrorists. He loves his family and will do anything to protect them, and his country. Francine: Stan's wife, she has had a past life of drugs, but she has carefully hidden her party-girl personality for the sake of the conservative man she loves. She met Stan after college. Hayley: The teenage daughter of the family, currently attending community college. Despite her father's best efforts she has turned out to be a left-wing liberal. Stan loves his daughter, but that doesn't necessarily mean he trusts her. Steve: The dorky son, he tries to act cool, but fails. Steve is on the verge of puberty - but he just can't quite make it. His low social status sometimes leads him to taking drastic action - but no matter what he does, he's just a dork. Roger: A sarcastic alien rescued by Stan from Area 51. He resents not being allowed to leave the house, so has resorted to drinking wine and smoking cigarettes. And Klaus: A German-talking goldfish, he was a CIA experiment that went horribly wrong when they tried transplanting a German man's brain into a goldfish. Klaus lusts after Francine, and will take any opportunity that comes his way.

Roger's voice is based on Paul Lynde.

Stanley Smith:
Why can't you take a page from that bitch Hillary Clinton and let it go?

Factual errors: In the first episode, the man whose brain was switched with Klaus's is shown at the 1986 Winter Olympics. There was no Winter Olympics in 1986; Winter Olympics were held in the same years as Summer Olympics (for example, 1984 in Sarajevo, and 1988 in Calgary) until 1994.